VI Molecular Cytopathology


Naples, 4 December 2017

Centro Congressi Partenope dell’Università Federico II di Napoli

Responsabile scientifico del Congresso: Prof. Giancarlo Troncone

Rationale

This congress aims to update the field of molecular predictive pathology focusing on diagnostic tests performed on histology, cytopathology and on blood samples. While until recently, pathological samples were only tested by sequential single-gene hotspot mutational tests, today, with the better understanding of the molecular events involved in malignancy and the mechanisms of pharmacotherapy, larger gene panels are more informative than a single biomarker detection.  A rapidly evolving field is also represented by the liquid biopsy and its application to guide treatment selection and follow-up of oncological patients in a number of neoplasms, including melanoma and lung cancer. In addition predictive tests in the field of immunotherapy need also to be discussed in order to standardize assays and biomarkers.

This congress addresses:

(1) the most relevant methodological and technical aspects of NGS analysis workflow and the diverse platforms available;

(2) the issues related to liquid biopsy daily practice implementation, namely, the pre-analytical sample requirement and the validation procedures;

(3) the opportunities that novel predictive biomarkers offers, to extend the analysis to a larger number of oncological patients. Pathologists’ involvement and coordination in this rapidly evolving field is crucial for the effective implementation of predictive pathology in the present and future clinical practice.